Presence of antibody against mouse fetal antigen in the sera from C57BL-6 mice immunized with Rauscher leukemia.
نویسندگان
چکیده
Presence of cross-reacting antibodies against embryonic cells and Rauscher leukemia cells was demonstrated in the sera collected from the C57BL/6 mice immunized with Rauscher leukemia cells, with the use of the indirect immunofluorescent test. Such cross-reacting antigenicity was also found in the SV40-transformed BLSV cells and AKR lymphoma cells. The antibody was completely absorbed with embryonic cells but not with adult spleen cells. Absorption tests showed that this antigen was different from Gross and FriendMoloney-Rauscher antigens. However, the cross-reacting antibodies were not detectable in the sera from 13-month-old mice in which the natural antibody against Gross antigen was clearly demonstrated.
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عنوان ژورنال:
- Cancer research
دوره 32 11 شماره
صفحات -
تاریخ انتشار 1972